Ellen DeGeneres, Portia De Rossi to separate?

Los Angeles: Funnywoman Ellen DeGeneres and partner Portia De Rossi, who have been married for seven years now, are reportedly calling it quits.

It is being said that Portia, 43, cheated on Ellen, 58, with a man, reported Aceshowbiz. "This is the end," a source close to the couple said. "Ellen and Portia have been squabbling and drifting apart for some time. But for Portia to leave Ellen for a man is the culmination of Ellen's worst fears."

Portia has apparently fallen in love with one of her "Scandal" co-stars. It's unknown who the man is. Ellen is reportedly gearing up for a USD 220 million divorce.

Ellen's ex-girlfriend Anne Heche left her for James Tupper after they dated for three years.

The TV host tied the knot with Portia on August 16, 2008 at their home in Los Angeles.